The past few decades have seen a significant growth in the field of supramolecular chemistry. During our study of supramolecular chemistry, we believe that an understanding of the genesis, attributes, and principles of mathematic geometry can provide a foundation for comprehending the structure design of supramolecular chemistry. And the connection between mathematic geometry and supramolecular chemistry appears to hold the key to an innovative and intriguing source from which to create a diverse array of structures to facilitate material applications. Our specific research interests include:
1) Design, synthesis and self-assembly of giant supramolecules using multitopic ligands, which provide more geometric constraints to prevent the formation of multiple entities and to reach the most thermodynamically stable architectures.
2) Incorporating a wide variety of functional groups into the supramolecular core structures through either pre- or post-assembly modification.
3) Characterization of supramolecules using mass spectrometry, e.g., Matrix-Assisted Laser Desorption/Ionization (MALDI), Electrospray Ionization (ESI), and Ion Mobility-Mass Spectrometry (IM-MS).
4) Exploring the applications of these assemblies in diverse fields, such as host−guest chemistry, molecular recognition, reactivity modulation, catalysis, template-directed synthesis and biology.